The increasing nicotine consumption is overwhelming in today’s society. There is a lot of controversy around the safety of nicotine. Some people consider nicotine a safer alternative to tobacco. However, the adverse effects of nicotine on various organ systems create a need for regulation of this compound, including collaborating with providers like Naked Smokes to promote the introduction of tobacco free cigarettes that may eliminate the addictive properties of the agent.
Nicotine is not only highly addictive but can pose severe impacts on systemic health. The initial effect of nicotine use is irritation and a burning sensation in the mouth and throat. Afterward, the user may experience increased salivation, nausea, abdominal pain, vomiting, and diarrhea. These gastrointestinal effects of nicotine occur upon cutaneous and respiratory exposure to the toxin, and severity depends on the amount taken. Therefore, relevant stakeholders in healthcare should promote awareness of nicotine’s rapid onset of action, making it one of the most toxic poisons.
Nicotine users face an increased risk of diabetes since the compound influences insulin resistance. There is also an association between chronic nicotine use and decreased body weight due to lipolysis. Nicotine forms arachidonic acid metabolites in the body, thus promoting cell division in normal cells, stimulating properties consistent with early stages of cancer, including higher cell proliferation, lower cellular dependence on the extracellular matrix for survival, and reduced contact inhibition.
Nicotine’s addictive property is the most problematic effect of the agent. This compound’s interaction with nicotinic acetylcholine receptors promotes dopamine transmission, stimulating the reward center. This affects mood elevation and causes improvements in cognitive performance. On the other hand, chronic stimulation by nicotine causes desensitization of GABAergic neurons inducing craving and thus promoting dependence.
At Naked Smokes, we recognize the need for efficient interventions against nicotine consumption, considering its highly addictive properties that can affect the CYP2A6 gene promoting heritable dependence on the compound. Our company introduces tobacco free cigarettes to encourage the use of herbal alternatives that may eliminate addiction and help consumers to quit smoking.
